England eked out four wickets in two sessions as they booked in for the long haul to try to bowl India out twice at the Ageas Bowl.
Stuart Broad struck twice before lunch on day three of the third Investec Test, and James Anderson and Moeen Ali added two afternoon successes, in the tourists' teatime 214 for five in reply to 569 for seven declared.
Ajinkya Rahane (52no) still stood principally in England's way, following up his Lord's century last week after an early stroke of fortune on eight when umpire Rod Tucker did not detect a glove down the leg-side to Jos Buttler off Moeen.
Alastair Cook had preferred Chris Woakes to Broad initially, in tandem with James Anderson this morning.
Broad, perhaps feeling a small point to prove, struck in his second over when he got a short ball to follow Cheteshwar Pujara and take the glove as the batsman tried to leave but instead gave England's new wicketkeeper Buttler his first catch in Test cricket.
Opener Murali Vijay was runless for 20 deliveries, Pujara scoring the first 20 runs of a glorious day.
It was Vijay who edged Anderson just short of second slip, resulting in a nasty blow to the left thumb and "acute bruising" but no fracture for Ian Bell - who stayed off the field thereafter.
Chris Jordan replaced Anderson but could not find his range from the northern end - so it was just as well for England that Broad was in the middle of a particularly testing spell, and one which proved too much for Vijay.
He had just beaten the opener on the outside as he pushed away from his body when, next ball, Vijay remained uncertain against a tight line and this time paid for it with an inside-edge down on to his stumps.
With Jordan still misfiring, Cook turned early to Moeen - a move which should have brought another wicket when Buttler took his second 'catch'.
Instead, it was not till after lunch that England struck again, Virat Kohli continuing his mediocre tour with 39 - his best score so far this summer - before edging Anderson to Cook at slip.
That appeared sure to be England's lot for the session until Rohit Sharma blundered, five minutes before tea, advancing to hit Moeen straight to Broad at mid off to end a stand of 74.