Wales coach Warren Gatland has made six changes from the team beaten by England for Saturday's RBS 6 Nations finale against Scotland in Cardiff.
Fly-half Rhys Priestland, hooker Richard Hibbard and prop Adam Jones are all relegated to the bench following the 29-18 defeat at Twickenham last weekend.
Dan Biggar replaces Priestland, with Scarlets forwards Ken Owens and Rhodri Jones preferred to Hibbard and Jones, respectively.
Elsewhere, Liam Williams takes over at full-back from dislocated shoulder victim Leigh Halfpenny, scrum-half Mike Phillips returns instead of Rhys Webb, who has an ankle injury, and fit-again lock Luke Charteris is in for Jake Ball.
Prop Gethin Jenkins, meanwhile, will set a new Wales cap record on Saturday when he makes his 105th Test match appearance.
Wales: L Williams (Scarlets); A Cuthbert (Cardiff Blues), J Davies (Scarlets), J Roberts (Racing Metro), G North (Northampton); D Biggar (Ospreys), M Phillips (Racing Metro); G Jenkins (Cardiff Blues), K Owens (Scarlets), R Jones (Scarlets), L Charteris (Perpignan), A-W Jones (Ospreys), D Lydiate (Racing Metro), S Warburton (Cardiff Blues, capt), T Faletau (Newport Gwent Dragons).
Replacements: R Hibbard (Ospreys), P James (Bath), A Jones (Ospreys), J Ball (Scarlets), J Tipuric (Ospreys), R Williams (Scarlets), R Priestland (Scarlets), J Hook (Perpignan).